MultiMiTar: A Novel Multi Objective Optimization based miRNA-Target Prediction Method
نویسندگان
چکیده
منابع مشابه
MultiMiTar: A Novel Multi Objective Optimization based miRNA-Target Prediction Method
BACKGROUND Machine learning based miRNA-target prediction algorithms often fail to obtain a balanced prediction accuracy in terms of both sensitivity and specificity due to lack of the gold standard of negative examples, miRNA-targeting site context specific relevant features and efficient feature selection process. Moreover, all the sequence, structure and machine learning based algorithms are...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0024583